Introduction: Hypertensive cardiopathy exhibits a high\nmorbidity and mortality worldwide. The complexity for its\nprevention depends on the number of risk factors involved.\nObjective: To design and validate a hypertensive\ncardiopathy predictive index based on risk factors which\npermit to predict the development of hypertensive cardiopathy\nin patients who suffer from arterial hypertension.\nMethod: An analytical study was carried out in which case\nand control hypertensive patients were paired off by sex and\nfollowed up by the Arterial Hypertensive Outpatient Department\nat ââ?¬Å?Carlos Manuel de CÃ?©spedesââ?¬Â General University Hospital\nof Bayamo, Granma, Cuba from January 1st, 2004 to December\n31st, 2009. The sample consisted of 1200 individuals. An index\nwas constructed based on independent risk factors and internal\nand external validation was carried out.\nResults: The logistic regression model showed that\nthe factor with greater importance was C-reactive protein\n(OR=10, 98; CI 95%=6.350-19,002; p=0,000) followed by\nglycemia greater than 5, 4 mmol/L (OR=5, 01); both the index\ndiscriminative capacity (area under the curve was 0,957; IC\n95%=0,934-0,980; p=0,000) and the calibration were adequate\n(Hosmer and Lemeshow; p=0,783). The validation process was\nsatisfactory.\nConclusion: Both indexes obtained and validated permit to\npredict accurately and reliably the development of hypertensive\ncardiopathy, so its introduction in clinical practice can improve\nthe evaluation of hypertensive patients.
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